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CHI3L2 — EPHB2

Text-mined interactions from Literome

Areshkov et al., Tsitol Genet 2010 (Glioblastoma) : Chitinase 3-like protein 2 ( CHI3L2, YKL-39 ) activates phosphorylation of extracellular signal regulated kinases ERK1/ERK2 in human embryonic kidney ( HEK293 ) and human glioblastoma ( U87 MG ) cells
Areshkov et al., International journal of biological sciences 2012 (MAP Kinase Signaling System) : In contrast to the activation of ERK1/2 phosphorylation by CHI3L1 that leads to a proliferative signal ( similar to the EGF effect in PC12 cells ), activation of ERK1/2 phosphorylation by CHI3L2 ( similar to NGF ) inhibits cell mitogenesis and proliferation