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RENBP — SMAD7

Text-mined interactions from Literome

Li et al., FASEB J 2004 (Diabetic Angiopathies...) : A substantial inhibition of AGE induced Smad activation and collagen synthesis by ERK/p38 MAPK inhibitors, but not by TGF-beta blockade, suggests that the MAPK-Smad signaling crosstalk pathway is a key mechanism in diabetic scarring ... Prevention of AGE induced Smad activation and collagen synthesis by overexpression of Smad7 indicates that Smad signaling may play a critical role in diabetic complications
Song et al., Exp Mol Med 2011 (Idiopathic Pulmonary Fibrosis) : Thus, the induction of Smad7 by the AGE-RAGE interaction limits the development of pulmonary fibrosis by inhibiting TGF-ß dependent signaling in AECs