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NBN — XIAP
Text-mined interactions from Literome
Ohnishi et al., Radiat Res 2006
(Carcinoma, Non-Small-Cell Lung) :
In addition, radiation induced expression of the transcription factor NF-kappaB (NFKB) and
XIAP ( X-chromosome linked inhibitor of apoptosis protein ) was
suppressed by
NBS1-siRNA
Rink et al., Blood 2007
(Leukemia) :
Expression of
Nbs1-S343A mutant disrupted the intra-S-phase checkpoint, decreased homologous recombinational repair ( HRR ) activity,
down-regulated XIAP expression, and sensitized BCR/ABL positive cells to cytotoxic drugs