Gene interactions and pathways from curated databases and text-mining

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NBN — XIAP

Text-mined interactions from Literome

Ohnishi et al., Radiat Res 2006 (Carcinoma, Non-Small-Cell Lung) : In addition, radiation induced expression of the transcription factor NF-kappaB (NFKB) and XIAP ( X-chromosome linked inhibitor of apoptosis protein ) was suppressed by NBS1-siRNA
Rink et al., Blood 2007 (Leukemia) : Expression of Nbs1-S343A mutant disrupted the intra-S-phase checkpoint, decreased homologous recombinational repair ( HRR ) activity, down-regulated XIAP expression, and sensitized BCR/ABL positive cells to cytotoxic drugs