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SOCS2 — STAT3

Pathways - manually collected, often from reviews:

• KEGG Jak-STAT signaling pathway: STAT1/STAT2/STAT3/STAT4/STAT5A/STAT5B/STAT6 → SOCS1/SOCS2/SOCS3/SOCS4/SOCS5/SOCS7 (gene expression, expression)
  
• WikiPathways Leptin Insulin Overlap: SOCS3/SOCS2/SOCS1 → STAT3/JAK2 (inhibition)

Text-mined interactions from Literome

Shen et al., FEBS Lett 2000 : Injection of IL-10 into mice activated STAT3 but not STAT1 tyrosine phosphorylation and induced suppressor of cytokine signal 2 (SOCS2) , SOCS3, and cytokine-inducible SH2 protein (CIS) mRNA expression in the liver
Sen et al., Clin Cancer Res 2012 (Carcinoma, Squamous Cell...) : STAT5A mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma ... SOCS2 inhibits Janus kinase 2 (Jak2) activity and Jak2-STAT3 binding ... SOCS2 expression is necessary for STAT3 inhibition by c-Src inhibitors