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EGF — IL1B
Text-mined interactions from Literome
Uchida et al., J Neurochem 1999
(Alzheimer Disease) :
Among interleukin-1beta (IL-1beta), fibroblast growth factor-2, epidermal growth factor (EGF), amyloid beta1-42, and 50 % O2, only EGF and
IL-1beta altered the level of GIF in confluent astrocytes :
EGF increased both GIF mRNA and protein, and IL-1beta decreased GIF mRNA, but did not alter GIF protein
Wan et al., Int J Mol Med 2001
(MAP Kinase Signaling System) :
IL-1 beta induced
EGF receptor tyrosine phosphorylation started at 5 min and peaked at 10 min and remained elevated up to 40 min post IL-1 beta treatment ... EGF receptor kinase inhibitor PD153035 and AG1478 inhibited
IL-1 beta induced
EGF receptor tyrosine phosphorylation
Deaciuc et al., Alcohol Clin Exp Res 2002
(Liver Diseases, Alcoholic) :
EGF did not
affect liver mRNA expression of TNF-alpha,
IL-1beta , IL-6, and IL-10, which suggested that these cytokines were not involved in EGF protective effect
Beales et al., Life Sci 2004
:
Gastrin and
IL-1beta stimulated the secretion of heparin binding
epidermal growth factor and amphiregulin but not transforming growth factor-alpha from parietal cells
Caillaud et al., Reprod Fertil Dev 2009
:
EGF induced an increase in the rate of in vitro maturation ( P < 0.05 ), whereas
IL-1beta had a limited effect
Le et al., J Exp Med 1991
:
Regulation of cytokine production in the human thymus :
epidermal growth factor and transforming growth factor alpha
regulate mRNA levels of interleukin 1 alpha (IL-1 alpha),
IL-1 beta , and IL-6 in human thymic epithelial cells at a post-transcriptional level ... Neither
EGF nor TGF-alpha
increased transcription rates of IL-1 alpha,
IL-1 beta , and IL-6 genes, but rather both EGF and TGF-alpha increased cytokine mRNA stability
Sirum et al., Biochemistry 1989
(Arthritis, Rheumatoid) :
In addition, using chimeric constructs of the stromelysin promoter linked to the bacterial gene chloramphenicol acetyltransferase (CAT), we show that the elements required for the tumor promoter phorbol myristate acetate ( PMA ),
epidermal growth factor (EGF) , and
interleukin 1 beta (IL-1 beta) induction are contained on a 307 base pair fragment which includes approximately 270 base pairs ( bp ) of 5'-flanking DNA
Demetri et al., Blood 1989
(Mesothelioma) :
Interleukin-1 beta (IL-1 beta) transcripts were
induced by
EGF , TNF, or LPS and were inhibited by hydrocortisone ( HC )
Sedlak et al., Chemotherapy 1994
(Breast Neoplasms) :
IL-1 beta and tumor necrosis factor alpha (TNF-alpha)
increased the
EGF receptor surface expression only on BT-20 breast carcinoma cells
Schluns et al., J Immunol 1997
:
TGF-beta differentially modulates
epidermal growth factor mediated increases in leukemia-inhibitory factor, IL-6, IL-1 alpha, and
IL-1 beta in human thymic epithelial cells
Li et al., J Cell Physiol 1997
:
Expression of KGF transcript was down-regulated by
EGF , TGF-alpha, and PDGF-BB, was markedly
up-regulated by
IL-1 beta , and was more pronounced in limbal than in corneal fibroblasts