Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
NR3C1
→
SRCAP
(directlyIncreases, SRCAP Activity)
Monroy et al., Mol Endocrinol 2003* Evidence: Our current studies demonstrate that SRCAP enhances PEPCK promoter transcription induced by glucocorticoids. SRCAP also enhances GR-mediated transcription of a simple promoter containing only two GRE elements, indicating that SRCAP functions as a GR coactivator.
OpenBEL Selventa BEL large corpus:
NR3C1
→
Complex of NCOA2-SRCAP
(directlyIncreases, NCOA2/SRCAP Activity)
Monroy et al., Mol Endocrinol 2003* Evidence: SRCAP Functions with CARM-1 and GRIP-1 to Synergistically Activate GR-Mediated Transcription