Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Li et al., Int J Neuropsychopharmacol 2007 (Disease Models, Animal...) : Taken together, these results demonstrate that PMS777 possesses dual activities for PAF receptor antagonism and AChE inhibition , suggesting that this compound may be a promising lead compound for further investigation related to the treatment for Alzheimer 's disease
Li et al., Cell Mol Neurobiol 2008 : PMS777, a bis interacting ligand for PAF receptor antagonism and AChE inhibition , attenuates PAF induced neurocytotoxicity in SH-SY5Y cells ... ( 2 ). We have previously reported that a novel tetrahydrofuran derived bis interacting ligand PMS777 had satisfying potencies for PAF receptor blockade and AChE inhibition , and markedly improved cholinergic dysfunction induced cognitive impairment in mice
Shukla et al., Life Sci 1986 : Action of phosphatidylinositol specific phospholipase C on platelets : nonlytic release of acetylcholinesterase , effect on thrombin and PAF induced aggregation