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MAPK1 — RIN1
Text-mined interactions from Literome
Barbieri et al., Eur J Cell Biol 2004
:
In contrast, expression of
Rin1 : delta, a natural splice variant of Rin1 lacking 47 amino acids in the Vps9p domain or Rab5,
increase both activation of
Raf-Erk1/2- and cyclin D1 transcription in response to EGF
Hunker et al., Exp Cell Res 2006
:
Interestingly, the expression of
Rin1 : wild type and both deletion mutants
blocks the activation of
Erk1/2 and Akt1 kinase activities without affecting either JN or p38 kinase activities ... In contrast, the expression of
Rin1 : delta
stimulates both
Erk1/2 and Akt1 activation, DNA synthesis and Elk-1 activation
Hunker et al., Anticancer Res 2006
:
Interestingly, the expression of
Rin1 selectively
blocked the activation of
Erk1/2 induced by the BCR/ABL oncogene