Chen et al., Science 2004
:
We find that two molecules interact with mammalian Smo in an activation dependent manner : G protein coupled receptor kinase 2 ( GRK2 ) leads to phosphorylation of Smo , and beta-arrestin 2 fused to green fluorescent protein interacts with Smo
Evron et al., J Biol Chem 2011
:
Gas8 knockdown in ciliated cells reduces Smo signaling activity and ciliary localization whereas overexpression stimulates Smo activity in a GRK2 dependent manner