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CSF2 — CXCR4

Text-mined interactions from Literome

Lee et al., Proc Natl Acad Sci U S A 1999 (HIV Infections) : We found that macrophage colony stimulating factor caused the greatest up-regulation of both CCR5 and CXCR4 on macrophage maturation ( from approximately 5,000 to approximately 50, 000 ABS ) whereas granulocyte-macrophage colony stimulating factor caused a marked decrease of CXCR4 ( from approximately 5,000 ABS to < 500 ) while up-regulating CCR5 expression ( from approximately 5,000 to approximately 20,000 ABS )
Iikura et al., J Leukoc Biol 2001 : IL-5, GM-CSF , and IL-4 also down-regulated CXCR4 expression
Nagase et al., J Leukoc Biol 2002 : IFN-alpha, granulocyte-macrophage colony stimulating factor ( GM-CSF ), and G-CSF also inhibited spontaneous CXCR4 expression
Zhao et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2005 : [ In vivo effect of rhG-CSF on the CXCR-4 expression of hematopoietic progenitor or stem cells in bone marrow and peripheral blood ]
Schutyser et al., Eur Cytokine Netw 2007 (Anoxia...) : CXCR4 mRNA expression was not affected by VEGF, GM-CSF , IL-1beta or various basal membrane matrix components, but was significantly up-regulated after serum starvation and/or hypoxic treatment of the microvascular endothelial cells
Di Campli et al., Dig Liver Dis 2007 (Chronic Disease...) : We aimed to evaluate safety and efficacy of granulocyte-colony stimulating factor treatment in patients with acute on chronic liver failure and the effect of granulocyte-colony stimulating factor on the expression level of CXCR4 , vascular endothelial growth factor receptor and very late activation antigen 4
Poppensieker et al., Proc Natl Acad Sci U S A 2012 (Encephalomyelitis, Autoimmune, Experimental...) : CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells
Di Marzio et al., AIDS Res Hum Retroviruses 1998 : GM-CSF , a cytokine that induces macrophage differentiation, caused a rapid decrease in CXCR4 and CCR5 mRNA and was correlated with decreased ability to support HIV entry