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GCH1 — IFNG

Text-mined interactions from Literome

Schroecksnadel et al., Clin Exp Immunol 2005 : In parallel, IFN-gamma induces enzyme GTP-cyclohydrolase I , which gives rise to neopterin production by activated human macrophages
Werner et al., Biochem J 1991 : Murine macrophages already contain high activities of GTP cyclohydrolase I when unstimulated, and this is further augmented up to 4-fold by tumour necrosis factor-alpha/interferon-gamma
Werner et al., Pathobiology 1991 : Interferon-gamma (IFN-gamma) induces the activity of GTP-cyclohydrolase I up to 40-fold in human cells
Werner et al., J Biol Chem 1990 : GTP-cyclohydrolase I is stimulated by interferon-gamma , and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present
Frank et al., J Invest Dermatol 1998 : Coordinated induction of inducible nitric oxide synthase and GTP-cyclohydrolase I is dependent on inflammatory cytokines and interferon-gamma in HaCaT keratinocytes : implications for the model of cutaneous wound repair