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EPHB2 — ITIH4

Text-mined interactions from Literome

Kuang et al., Eur J Immunol 2012 (HIV Infections) : Here, we show that NHERF1 can associate with CCR5, and promote activation of the gp120 induced MAPK/ERK , focal adhesion kinase and RhoA ( Ras homolog gene family member A ) signaling pathways
Spadaro et al., PloS one 2013 : Notably, phosphatidylcholine-specific phospholipase C ( PC-PLC ), previously reported to be required for NF-kB mediated CCL2 production induced by gp120 in macrophages, drives both ERK1/2 activation and PI-PLC ß1 nuclear localization induced by gp120
Lannuzel et al., Ann Neurol 1997 (AIDS Dementia Complex) : Human immunodeficiency virus type 1 and its coat protein gp120 induce apoptosis and activate JNK and ERK mitogen activated protein kinases in human neurons ... Gp120 activated c-Jun N-terminal kinase (JNK) and p42 extracellular regulated kinase (ERK) in primary CNS cells, with an early peak of activation at 2 to 5 minutes that was not present when pure microglial or astrocyte cultures were tested, followed by a late and sustained activation ( 10 and 60 minutes ) in primary and enriched glial cell cultures as well as in transformed microglial cells