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MYO9B — RHOA

Pathways - manually collected, often from reviews:

• NCI Pathway Database Regulation of RhoA activity: Myosin IXB (MYO9B) → RHOA/GTP complex (RHOA) (modification, activates) Post et al., J Cell Sci 1998*
  Evidence: assay
• Reactome Reaction: RHOA → MYO9B (reaction) Richnau et al., J Biol Chem 2001, Krugmann et al., Mol Cell 2002, Tcherkezian et al., Biol Cell 2007, Fainstein et al., Nature 1987, Lancaster et al., J Biol Chem 1994, Yuan et al., Cancer Res 1998

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: MYO9B — RHOA (direct interaction, pull down) Saeki et al., J Biol Chem 2005*

Text-mined interactions from Literome

Saeki et al., J Biol Chem 2005 : Likewise, RhoA inhibited the BIG1 binding of myosin IXb
Long et al., Cereb Cortex 2013 : These data demonstrate that Myo9b and RICS repress RhoA/Rock signaling and modulate dendritic morphogenesis in cortical neurons, providing evidence for critical physiological function of RhoA GAPs in regulation of dendritic development