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CDKN1A — PDCD6
Text-mined interactions from Literome
Park et al., Cell Signal 2012
(Ovarian Neoplasms) :
The
p21 and p53 promoter luciferase activities were
enhanced by
PDCD6 , while there was no affect in p53 ( -/- ) and p21 ( -/- )
Cox et al., J Pathol 1997
(Cell Transformation, Neoplastic) :
Current research highlights the action of a p53 activated gene, p21Cip1/WAF1/Sdi1, which encodes a cyclin-kinase inhibitor important in mediating p53 dependent cell-cycle arrest, while
programmed cell death in response to DNA damage
requires transcriptionally active p53 but not activation of
p21Cip1/WAF1/Sdi1