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CTNNB1 — LIN37
Text-mined interactions from Literome
Perego et al., EMBO J 2000
:
The association of LIN-7 with cadherin and
beta-catenin is Ca ( 2+ ) dependent and is
mediated by the direct binding of
LIN-7 to the C-terminal PDZ target sequence of beta-catenin, as demonstrated by means of co-immunoprecipitation experiments and in vitro binding assays with the recombinant glutathione S-transferase : LIN-7A ... The presence of beta-catenin at the junction is required in order to relocate LIN-7 from the cytosol to cadherin mediated adhesions, thus indicating that
LIN-7 junctional recruitment is
beta-catenin dependent and that one functional role of the binding is to localize LIN-7
Dreier et al., Neuron 2005
:
LIN-23 mediated degradation of
beta-catenin regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans ... We hypothesize that
LIN-23 mediated degradation of BAR-1
beta-catenin regulates the transcription of Wnt target genes, which in turn alter postsynaptic properties