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MXI1 — MYC

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: MYC → MXI1 (decreases, MXI1 Activity)
  Evidence: HIF1 also directly induces MXI1 (FIG. 1), which competes for and binds MAX, thereby antagonizing MYC function25,46.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: MXI1 — MYC (two hybrid) Estojak et al., Mol Cell Biol 1995*

Text-mined interactions from Literome

Corn et al., Cancer Biol Ther 2005 : The results suggest a coordinated mechanism for opposing c-Myc signaling during hypoxia that is mediated by a reduction in c-Myc levels, the induction of Mxi1 , and a dominant effect of HIF-1 transcriptional activity
Dugast-Darzacq et al., FEBS J 2007 : Furthermore, although Mxi1-SRbeta exhibits a repressive effect on the MYC promoter in transient expression assays, Mxi1-SRalpha activates this promoter