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MYC — PLD2

Text-mined interactions from Literome

Chen et al., Oncogene 2003 (Adenocarcinoma...) : Elevated PLD activity in MCF-7 cells also caused rapamycin resistance for S6 kinase phosphorylation and serum induced Myc expression
Rodrik et al., Mol Cell Biol 2005 (Breast Neoplasms) : Stable elevated expression of PLD2 also increased Myc expression and provided a Myc dependent survival signal in the absence of E2
Rodrik et al., FEBS Lett 2006 (Breast Neoplasms) : We report here that estrogen- and PLD induced increases in Myc expression are due to reduced turnover of Myc protein ... Estrogen and PLD suppressed phosphorylation of Myc at Thr58 -- a site that targets Myc for degradation by the proteasome