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ERBB2 — ERBB2IP

Pathways - manually collected, often from reviews:

• Reactome Reaction: ERBB2 → ERBB2IP (direct_complex) Xu et al., Proc Natl Acad Sci U S A 2002, Ehrlich et al., Proc Natl Acad Sci U S A 2009
• Reactome Reaction: ERBB2 → ERBB2IP (reaction) Borg et al., Nat Cell Biol 2000, Xu et al., J Biol Chem 2001, Citri et al., EMBO Rep 2004, Xu et al., Nature structural & molecular biology 2005, Li et al., Cell Signal 2007, Wada et al., Cell 1990, Karunagaran et al., EMBO J 1996, Pinkas-Kramarski et al., EMBO J 1996
• WikiPathways Pathways Affected in Adenoid Cystic Carcinoma: ERBB2IP → ERBB2 (activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: ERBB2IP — ERBB2 (physical association, affinity chromatography technology) Jaulin-Bastard et al., J Biol Chem 2001*
• IRef Biogrid Interaction: ERBB2IP — ERBB2 (direct interaction, two hybrid) Jaulin-Bastard et al., J Biol Chem 2001*
• IRef Biogrid Interaction: ERBB2IP — ERBB2 (direct interaction, pull down) Jaulin-Bastard et al., J Biol Chem 2001*
• IRef Biogrid Interaction: ERBB2IP — ERBB2 (physical association, affinity chromatography technology) Borg et al., Nat Cell Biol 2000
• IRef Biogrid Interaction: ERBB2IP — ERBB2 (direct interaction, pull down) Borg et al., Nat Cell Biol 2000
• IRef Biogrid Interaction: ERBB2IP — ERBB2 (physical association, affinity chromatography technology) Huang et al., J Biol Chem 2003*
• IRef Hprd Interaction: ERBB2IP — ERBB2 (in vitro) Borg et al., Nat Cell Biol 2000, Jaulin-Bastard et al., J Biol Chem 2001*
• IRef Hprd Interaction: ERBB2IP — ERBB2 (in vivo) Borg et al., Nat Cell Biol 2000, Jaulin-Bastard et al., J Biol Chem 2001*
• IRef Innatedb Interaction: ERBB2 — ERBB2IP (unknown, -) Liu et al., J Biochem 2008*
• IRef Ophid Interaction: ERBB2 — ERBB2IP (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Borg et al., Nat Cell Biol 2000 : We suggest that ERBIN acts in the localization and signalling of ERBB2/HER2 in epithelia
Huang et al., J Biol Chem 2001 : Expression of Erbin increases the amount of ErbB2 labeled by biotin in transfected cells, suggesting that Erbin is able to increase ErbB2 surface expression
Liang et al., J Neurosci 2012 (Disease Models, Animal...) : Together, these observations demonstrate that Erbin is required for remyelination of regenerated axons after injury, probably by regulating ErbB2 and NRG1 levels, identifying a novel player in regulating remyelination