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CRH — UCN2
Text-mined interactions from Literome
Nijsen et al., Neurogastroenterol Motil 2005
(Pain) :
Selective
activation of the
CRF2 receptor by
stresscopin related peptide ( SRP ; i.p. 25 microg kg-1 ) reduced the distension induced visceromotor and behavioural response
Nemoto et al., J Endocrinol 2007
:
In the anterior pituitary cells,
corticotropin releasing factor (CRF)
increased mRNA expression levels and secretion of
Ucn 2 , although arginine vasopressin (AVP) did not induce any significant change in Ucn 2 expression or secretion ... In the intermediate pituitary,
CRF increased both the mRNA expression levels and secretion of
Ucn 2 ... These results suggest that the mRNA expression and secretion of
Ucn 2 in POMC cells of the pituitary are positively
regulated by
CRF and negatively regulated by glucocorticoids
Nemoto et al., J Endocrinol 2009
:
We previously demonstrated that Ucn 2 is expressed in the corticotrophs of rat pituitary, and the mRNA expression and secretion of
Ucn 2 in corticotrophs of rat anterior pituitary are
regulated by
CRF and glucocorticoids
Kageyama et al., Frontiers in endocrinology 2013
:
In corticotrophs, stress induced increases in
CRF stimulate
Ucn2 production, which leads to the inhibition of gonadotropin secretion via the CRF ( 2 ) receptor in the pituitary