Gene interactions and pathways from curated databases and text-mining

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HBD — IL8

Text-mined interactions from Literome

Griffin et al., FEBS Lett 2003 : Human beta-defensin-2 (HBD-2) gene expression is induced by tumour necrosis factor-alpha, interleukin-1beta and lipopolysaccharide
Sakamoto et al., Am J Physiol Lung Cell Mol Physiol 2005 : The results showed that treatment of HBECs with HNP-1, but not HBD-2 , increased IL-8 and IL-1beta mRNA expression in a dose dependent manner and also enhanced IL-8 protein secretion and NF-kappaB DNA binding activity