Gudmundsdottir et al., EMBO Rep 2004
(Genomic Instability) :
DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells ... However, DSS1 seems to be not required for BRCA2 or RAD51 stability or for BRCA2 and RAD51 to interact, raising the possibility that DSS1 may be required for the BRCA2-RAD51 complex to become associated with sites of DNA damage
Kojic et al., Mol Cell Biol 2005
:
The results provide evidence for a mechanism in which Dss1 activates a Brh2-Rad51 complex and balances a finely regulated recombinational repair system
Zhou et al., Mol Cell Biol 2007
:
Brh2, the BRCA2 ortholog in Ustilago maydis, enables recombinational repair of DNA by controlling Rad51 and is in turn regulated by Dss1