Gene interactions and pathways from curated databases and text-mining

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E2F7 — E2F8

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Di Stefano et al., EMBO J 2003 : Interestingly, however, E2F7 binds only a subset of E2F dependent promoters in vivo, and in agreement with this, inhibition of E2F7 expression results in specific derepression of these promoters
Christensen et al., Nucleic Acids Res 2005 : Ectopic expression of E2F8 in diploid human fibroblasts reduces expression of E2F-target genes and inhibits cell growth consistent with a role for repressing E2F transcriptional activity