◀ Back to SHH

BMP1 — SHH

Text-mined interactions from Literome

Liem et al., Development 2000 : Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites
Ohkubo et al., Neuroscience 2002 (Abnormalities, Drug-Induced...) : Similarly, loss of SHH expression in Shh mutant mice leads to increased BMP signaling and loss of Fgf8 expression in the prosencephalon
Harris et al., J Exp Zool 2002 : We show that Shh signaling is necessary for the formation and proper differentiation of a barb ridge and that it is mediated by Bmp signaling ... BMP signaling is necessary and sufficient to negatively regulate Shh expression within forming feather germs and this epistatic relationship is conserved in scale morphogenesis
Anderson et al., Development 2002 (Craniofacial Abnormalities...) : Ectopic application of BMP2 to wild-type cephalic explants results in decreased FGF8 and SHH expression in rostral tissue, suggesting that the decreased expression of FGF8 and SHH observed in vivo is due to ectopic BMP activity
Sharov et al., Am J Pathol 2009 (Cell Transformation, Neoplastic...) : Furthermore, BMP signaling stimulated Wnt inhibitory factor-1 expression and promoter activity in cultured tumor cells and HaCaT keratinocytes, as well as inhibited Shh expression, as compared with the corresponding controls
Huang et al., J Bone Miner Res 2010 : At the molecular level, Smad4 mediated TGF-beta/BMP signaling is required for Shh expression in HERS and Nfic ( nuclear factor Ic ) expression in the cranial neural crest (CNC) derived dental mesenchyme
Nishimori et al., J Biol Chem 2012 (Bone Neoplasms...) : In human prostate cancer LNCaP cells, BMP-4 induced the production of Sonic hedgehog (SHH) through a Smad dependent pathway
Hofmann et al., Dev Genet 1996 (Congenital Abnormalities...) : Here we show that Hoxd-11 expression domains are also contracted and decreased in intensity in mutant limbs, suggesting that 5 ' genes of the Hoxd cluster are coordinately downregulated, while another Bmp , Bmp-2, which can be activated by Shh , is similarly expressed
Yang et al., Development 1997 : However, Shh induces dose dependent expression of Bmp genes in anterior mesenchyme at the start of the promotion phase