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APOB — LRPAP1

Text-mined interactions from Literome

Troussard et al., J Biol Chem 1995 : Studies on the interaction of RAP with LSR in isolated rat liver membranes revealed that at concentrations > or = 10 micrograms/ml, RAP inhibited in a dose dependent manner the binding of LDL to LSR ; half-maximum inhibition was obtained with 20 micrograms/ml RAP
Medh et al., J Biol Chem 1995 : In normal human foreskin fibroblasts, RAP inhibited LDL receptor mediated binding and catabolism of LDL and VLDL with Sf 20-60 or 100-400 ... RAP inhibited 125I labeled LDL and Sf 100-400 lipoprotein binding at 4 degrees C with KI values of 60 and 45 nM, respectively ... Also, RAP inhibited 125I labeled LDL and Sf 100-400 VLDL binding to LDL receptors in solid-phase assays with KI values of 140 and 130 nM, respectively ... Because LDL bind via apolipoprotein ( apo) B100 whereas VLDL bind via apoE, our results show that RAP inhibits LDL receptor interactions with both apoB100 and apoE
Wu et al., Arch Biochem Biophys 1996 : alpha 2M* and RAP can inhibit the binding of LDL to macrophages completely ( 96 and 100 % inhibition, respectively ), after cell surface heparin has been removed by treatment with heparinase