Gene interactions and pathways from curated databases and text-mining

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KRAS — PDK1

Text-mined interactions from Literome

CarĂ³n et al., Mol Cancer Ther 2005 (Carcinoma...) : Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1 , and AKT and the effect of therapeutic kinase inhibitors on cell survival
Wang et al., Cancer Res 2013 (Breast Neoplasms...) : In addition, Pdk1 activation of the downstream effector p90RSK is also increased by the combined presence of mutant KRAS and PIK3CA