Gilmore et al., Breast Cancer Res Treat 2008
(Breast Neoplasms) :
Amphiregulin-EGFR signaling regulates PTHrP gene expression in breast cancer cells ... It has been previously shown that EGFR signaling induces the production of PTHrP in several primary and transformed epithelial cell types
Gilmore et al., Mol Cancer Res 2009
(Bone Neoplasms...) :
Finally, ectopic expression of EGFR in a receptor-low but AREG expressing cell line increased PTHrP mRNA levels in vitro, and induced the capability to cause HHM and rapid osteolytic growth in vivo
Alsat et al., J Cell Biochem 1993
:
This led us to study the effect of PTH ( 1-34 ) and PTHrP ( 1-34 ) on the expression of EGFR during this differentiation process