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IL21 — IL7

Text-mined interactions from Literome

Allard et al., Eur J Immunol 2007 : We show that IL-21 inhibits IL-7R expression on naive T cells in vitro, suggesting impaired IL-7 mediated naive T cell survival in IL-21-transgenic mice
Caprioli et al., J Immunol 2008 (Crohn Disease...) : Additionally, both IL-7 and IL-15, but not IL-4, induce IL-21 , thus suggesting that common gamma-chain signals are not sufficient to promote IL-21 synthesis
Nakayamada et al., Immunity 2011 : Herein, we showed interleukin-12 acting via the transcription factor STAT4 induced both Il21 and Bcl6 genes, generating cells with features of both Tfh and Th1 cells