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APOB — BGN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Chang et al., Arterioscler Thromb Vasc Biol 2003
:
Ox-LDL specifically
upregulates biglycan expression while causing elongation of glycosaminoglycan chains on all of the major secreted proteoglycans ( biglycan, decorin, and versican ), resulting in enhanced lipoprotein binding interactions ... Lysophosphatidylcholine mimics the ability of
Ox-LDL to
stimulate biglycan expression and also causes a marked induction of the core protein for the proteoglycan form of macrophage colony stimulating factor
Hiukka et al., Diabetes 2009
(Diabetes Mellitus, Type 2...) :
ApoCIII enriched
LDL in type 2 diabetes displays altered lipid composition, increased susceptibility for sphingomyelinase, and
increased binding to
biglycan