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BSG — PLAU
Text-mined interactions from Literome
Quemener et al., Cancer Res 2007
(Breast Neoplasms...) :
Enhanced
EMMPRIN expression in a tumorigenic breast epithelial cell line NS2T2A
increased the levels of
uPA , uPA receptor, and the uPA inhibitor plasminogen activator inhibitor-1 ( PAI-1 ), as measured by quantitative reverse transcription-PCR, Western blot, and plasminogen-casein zymography ... Additionally, overexpression of
EMMPRIN in NS2T2A cells
increased uPA levels in cocultured endothelial cells, showing a paracrine regulation loop involving a tumor-stroma interaction
Lescaille et al., BMC cancer 2012
(Carcinoma, Squamous Cell...) :
In this study, the
role of
EMMPRIN in regulating
uPA and invasion was investigated in oral squamous cell carcinoma ( OSCC ) progression ... The paracrine
regulation of
uPA by
EMMPRIN was investigated by treating culture cells with EMMPRIN enriched membrane vesicles