Gene interactions and pathways from curated databases and text-mining

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IL21 — SOCS3

Text-mined interactions from Literome

Strengell et al., J Leukoc Biol 2006 : However, IL-21 strongly stimulated the expression of suppressor of cytokine signaling (SOCS)-1 and SOCS-3 genes
Qin et al., J Immunol 2009 : In this report, we demonstrate that TGF-beta inhibits IL-6- and IL-21 induced SOCS3 expression, thus enhancing as well as prolonging STAT3 activation in naive CD4 ( + ) CD25 ( - ) T cells
Kleinsteuber et al., Blood 2012 (Tuberculosis) : SOCS3 promotes interleukin-17 expression of human T cells
Romain et al., Arterioscler Thromb Vasc Biol 2013 (Aortic Aneurysm, Abdominal...) : Overexpression of SOCS3 in T lymphocytes leads to impaired interleukin-17 production and severe aortic aneurysm formation in mice -- brief report