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CCND2 — IL2

Text-mined interactions from Literome

Martino et al., J Immunol 2001 : Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2 ... We propose that the IL-2R regulates the cyclin D2 gene in part through formation of an enhancer complex containing Stat5 and Sp1
Mouhamad et al., Eur Cytokine Netw 2002 : zVAD-fmk inhibits IL-2 induced phosphorylation of the retinoblastoma protein, and cyclin D2 expression
Nelson et al., J Immunol 2003 : IL-2 induces c-myc, cyclin D2 , and cyclin E in a redundant manner through the Shc and STAT5 pathways
White et al., Oncogene 2006 (Cell Transformation, Viral) : The introduction of an S133A mutant of CREB-1 reduces IL-2 induction of cyclin D2 promoter activity, demonstrating a role for this phosphorylation site in promoter activity