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RHOA — TYR

Text-mined interactions from Literome

Debidda et al., J Biol Chem 2005 (Inflammation) : We also found that although active RhoA , Rac1, and Cdc42 could all mediate Ser-727 and Tyr-705 phosphorylation and nuclear translocation of STAT3, the Rho GTPases were able to induce STAT3 activation independently of the interleukin-6 autocrine pathway, and active RhoA, Rac1, or Cdc42 could not form a stable complex with STAT3 as previously suggested, indicating an unappreciated mechanism of STAT3 activation by the Rho GTPases
Chaturvedi et al., Am J Physiol Cell Physiol 2011 (MAP Kinase Signaling System...) : Furthermore, RhoA, ROCK inhibition or RhoA , ROCK1, ROCK2, and mDia1 reduction by siRNA also blocked strain induced FAK-Tyr ( 925 ), p38, and MLC phosphorylation
Haidari et al., Exp Cell Res 2012 : Atorvastatin inhibited IL-1ß induced Tyr phosphorylation of VE-cad by inhibiting RhoA and by dephosphorylating MLC ... Our study introduces a novel pleiotropic effect of atorvastatin and suggests that statins protect the integrity of AJs in ECs by inhibiting RhoA mediated Tyr phosphorylation of VE-cad